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NICE technology appraisals

2010-06-28: NICE technology appraisals

NICE technology appraisals have been published on:

  • Human growth hormone (somatropin) as a possible treatment for some children with growth failure (review)

MHRA - Information sent to healthcare professionals in May

2010-05-28: MHRA - Information sent to healthcare professionals in May

The MHRA sent letters to healthcare professionals in May 2010 to inform of new safety information and advice.

  • Perfalgan® (intravenous paracetamol)
  • Keppra® (levetiracetam)

MHRA - Information sent to healthcare professionals in April

2010-04-28: MHRA - Information sent to healthcare professionals in April

The MHRA sent letters to healthcare professionals in April 2010 to inform of new safety information and advice.

  • Fabrazyme® (agalsidase beta)
  • Cerezyme® (imiglucerase)

MHRA - Information sent to healthcare professionals in March

2010-04-14: MHRA - Information sent to healthcare professionals in March

The MHRA sent letters to healthcare professionals in March 2010 to inform of new safety information and advice.

  • Regranex® (becaplermin)
  • Fungizone® (parenteral amphotericin B)
  • Rifadin® for infusion 600mg (rifampicin)

BNF Publications need your feedback

2010-03-22: BNF Publications need your feedback

BNF Publications has set up ‘Virtual User Group’s’ that enable healthcare professionals to provide feedback on using the BNF and BNF for Children. Brief questionnaires will be available via the BNF/BNF for Children e-newsletters. Practising professionals who would like to contribute can simply follow the link below. Thank you in advance and we look forward to receiving your comments and contributions. The survey will close on 31.3.10.

Click here to take part.

BNF 59 (March 2010) is published

2010-03-17: BNF 59 (March 2010) is published

Information about changes made for this edition is available here.

NPSA urges neonatal services to follow new gentamicin safety guidance

2010-03-04: NPSA urges neonatal services to follow new gentamicin safety guidance

New guidance, produced by the National Patient Safety Agency (NPSA) and NHS organisations across England and Wales, has been issued aimed at ensuring safer systems are in place to care for newborn babies needing treatment with gentamicin.

MHRA - Information sent to healthcare professionals in February

2010-03-04: MHRA - Information sent to healthcare professionals in February

The MHRA sent letters to healthcare professionals in February 2010 to inform of new safety information and advice.

  • Rapamune® (sirolimus)
  • Protopic® (topical tacrolimus)
  • Advagraf®, Prograf® and Modigraf® (oral tacrolimus)
  • Fabrazyme® (agalsidase beta)
  • Cerezyme® (imiglucerase)

UK Anti-Doping (UKAD)

2010-02-22: UK Anti-Doping (UKAD)

The new organisation, UK Anti-Doping (UKAD), assumes responsibility from UK Sport as the National Anti-Doping Organisation for the UK.The UKAD website contains links to the current World Anti-Doping Agency (WADA) Prohibited List and to the Global Drug Reference Online, which provides athletes and support personnel with information about the prohibited status of specific substances based on the current WADA Prohibited List.

BNF Publications achieve ISO9001:2008 certification

2009-11-04: The BNF quality management system achieves ISO9001:2008 certification

BNF Publications are delighted to announce that SGS, one of the world leaders in quality management assessment, has confirmed that the BNF quality management system (QMS) has achieved ISO9001:2008 certification.

Through formalisation of working processes, ISO9001:2008 QMS provides assurance about the ability to satisfy quality requirements and to enhance customer satisfaction.

Duncan Enright, Publishing Director at the BNF, said:
"This certification will allow us to use the ISO9001:2008 as a mark of quality. It demonstrates to others our robust processes and controls, it allows us to meet other compliance challenges more easily as they emerge, and most importantly, it lets us develop and seek efficiencies most effectively."

New BNF published

2009-09-16: BNF 58 (September 2009) is published

Information about changes made for this edition is available here.

The new BNF for Children (BNFC) - delivering the latest advice on recent health concerns

2009-07-10: The fifth edition of BNF for Children (BNFC 2009) has been published

The fifth edition of BNF for Children (BNFC) arms health professionals with the information they need to tackle a wide range of health concerns, especially those relating to neonatal intensive care and flu in very young children.

BNFC contains new guidance on the use of oseltamivir for children suffering from influenza under the age of one, safety advice to avoid dosage errors when caffeine is used to treat neonatal apnoea, and an entire new appendix on intravenous infusions for neonatal intensive care.

This edition, new tables have also been produced to provide practical information on the management of acute asthma, and on ACBS-approved enteral feeds, nutritional supplements, and special feeds for children with different nutritional requirements.

John Martin, Managing Editor of BNF publications said:

"Just as health professionals will not give children out of date medicines, neither should they rely on out of date information for prescribing medicines. Instead they should turn to the latest edition of BNFC for clear, practical guidance on all aspects of paediatric drug therapy.

The BNFC has been extensively revised and updated, validated by national experts in paediatrics, and improved in response to constructive comments from paediatricians, GPs, nurses, pharmacists, dentists and dieticians who have been using it to help them treat children safely and effectively over the last five years."

To help health professionals put some of the new therapeutic advice into practice, the next BNF and BNFC e-newsletter will include a case study on otitis media, immunisations, and nutrition.

Medicines for Children information leaflets for parents and carers

2009-06-02: Medicines for Children information leaflets

http://www.medicinesforchildren.org.uk/

The Medicines for Children website was launched in April 2009. It provides information leaflets specifically about the use of medicines in children. They have been written for parents and carers but are also suitable for older children.

The leaflets have been developed under a joint initiative by the Royal College of Paediatrics and Child Health (RCPCH), Neonatal and Paediatric Pharmacists group (NPPG) and WellChild.

NICE technology appraisals

2009-03-11: A NICE technology appraisal is available for amantadine, oseltamivir and zanamivir for the treatment of influenza (review of existing guidance No. 58)

NPSA issue rapid response report

2009-03-11: The NPSA has issued a rapid response report on reducing risk of harm from oral bowel cleansing solutions (NPSA/2009/RRR012)

MHRA advice

2009-03-11: The MHRA has issued advice on over-the-counter cough and cold medicines for children

MHRA - Efalizumab (Raptiva®): Recommendation to suspend marketing authorisation as risks outweigh benefits

2009-02-24: The European Medicines Agency has completed a review of efalizumab (Raptiva®) after concerns about its safety. The Agency’s Committee for Medicinal Products for Human Use (CHMP) has concluded that the benefits of efalizumab do not outweigh its risks, and that the marketing authorisation should be suspended across the EU.

MHRA - Information sent to healthcare professionals in January

2009-02-18: The MHRA sent letters to healthcare professionals about Sustiva® and Stocrin® (efavirenz) in January 2009, to inform of new safety information and advice

MHRA - Information sent to healthcare professionals in November

2008-12-12: The MHRA sent letters to healthcare professionals about Mabthera® (rituximab) in November 2008, to inform of new safety information and advice

Job Vacancies for BNF publications

2008-11-19: Due to internal promotions and the expansion of the editorial team, BNF publications are currently recruiting Clinical Pharmacists to work as staff editors for BNF and BNF for Children.

If you feel you would to take up this challenging but rewarding opportunity, further details and how to apply can be found at bnf.org/jobs.

MHRA—Information sent to healthcare professionals in October

2008-11-11: The MHRA sent letters to healthcare professionals about Arcoxia® (etoricoxib) in October 2008, to inform of new safety information and advice.

NICE technology appraisals

2008-10-07: A NICE technology appraisal is available for Influenza prophylaxis

New BNF published

2008-09-11: BNF 56 (September 2008) is published

Information about changes made for this edition is available here.

NPSA issue rapid response report

2008-08-11: The NPSA has issued a rapid response report on new guidance for injecting adults and adolescent patients with intravenous cancer drug (NPSA/2008/RRR004).

Updated national guidance on the safe administration of intrathecal chemotherapy

2008-08-11: The Chief Medical Officer has issued a Health Service Circular (2008/001) which covers the updated National Guidance on the Safe Administration of Intrathecal Chemotherapy. The updated guidance replaces HSC 2003/010.

The guidance cross-refers to the National Patient Safety Agency (NPSA) rapid response report (NPSA/2008/RRR004) on the use of vinca alkaloid minibags that should be read in conjunction with this document.

National MMR vaccine catch-up campaign launched

2008-08-07: The Department of Health is making extra vaccine and more funds available to help local health trusts start a campaign to vaccinate every child up to the age of 18 against measles. For further details visit Department of Health, News.

NPSA issue rapid response report

2008-07-14: The NPSA has issued a rapid response report on Reducing Dosing Errors with Opioid Medicines

BNF for Children 2008 is published

2008-07-03: The fourth edition of BNF for Children (BNFC 2008) has been published

The fourth edition of the BNF for Children (BNFC) arms health professionals with the information they need to tackle recent controversial health concerns in young people, including rising rates of teenage pregnancy and the increasing incidence of sexually transmitted infections.

Professor Martin Kendall, Chairman of the Formulary Development Committee, said:

“This year, to protect young people from cervical cancer, updated advice on human papilloma virus vaccine which will be offered to all girls aged 12–13 years from September, has been included. Also, noting the national concerns about sexual activity in the young, BNFC 2008 has new sections on contraception and additional guidance on the treatment of sexually transmitted infections. The BNFC is the national guide on managing the diseases of today and protecting children and young people from the medical problems of tomorrow.

The BNFC has been extensively revised and updated, checked by national experts and improved by the comments of paediatricians, nurses, pharmacists and dentists who have been using it to help them treat children safely and effectively over the last four years.”

The new edition of the BNF for Children is published today by the BMJ Group, the Royal Pharmaceutical Society of Great Britain, the Royal College of Paediatrics and Child Health, and the Neonatal and Paediatric Pharmacists Group.

BNFC 2008 has been fully revised and improved. The changes include:

  • Details of a new immunisation schedule for vaccination against the human papilloma virus
  • Revised guidance on the treatment and prevention of urinary-tract infections
  • New advice on the use of all forms of contraception, including emergency contraception
  • A new section on the treatment of pelvic inflammatory disease to further expand the guidance on management of sexually transmitted infections
  • More information on the administration of continuous IV infusions in neonatal intensive care to reduce medication errors when calculating infusion rates.

The BNFC is available in print, and on PDA. Further details about these and other changes can be found free of charge at http://bnfc.org/bnfc/bnfcextra/current/450035.htm

Dr Patricia Hamilton, President, of the RCPCH comments: "The Royal College of Paediatrics and Child Health is proud to be a partner in producing the BNF for Children which is an essential resource for paediatricians and other healthcare professionals.

It is important to highlight the new emphasis on adolescent health, with information in this edition on contraception, the treatment of sexually transmitted diseases and a vaccination which protects against cervical cancer. The BNFC will also contribute to patient safety by ensuring users have the most up-to-date information and guarding against medication errors."

Independent market research confirms the high standing of BNF for Children

2007-08-01: The growing importance of BNF for Children is highlighted in recent research conducted by Taylor Nelson Sofres on behalf of the publishers

The growing importance of BNF for Children is highlighted in recent research conducted by Taylor Nelson Sofres on behalf of the publishers. The attributes rated most highly by users are the BNFC's trustworthiness, authority, accessibility and independence, and the data implies that the BNFC is providing ‘reassurance’ to 97% of its recipients

BNFC is the first resource that 74% of healthcare professionals turn to when seeking information about the use of medicines in children.

BNFC is used at least once a day or more by 82% of hospital nurses, 46% of hospital doctors and 38% of hospital pharmacists.

Seventy percent of recipients have become more aware of suitable medicines and treatments as a result of using BNFC and 40% believe that BNFC has changed their clinical practice. For 53% of recipients, BNFC has reduced the number of times that they need to seek advice from other healthcare professionals.

In the view of almost half the recipients, BNFC has led to an improvement in the quality of prescribing for children under shared care arrangements between primary and secondary care.

This support for BNF for Children follows the backing given to the BNF by healthcare professionals in a recent survey which found that the BNF is used over 3 million times a week.

Dr Patricia Hamilton, President of the Royal College of Paediatrics and Child Health said, “The Royal College of Paediatrics and Child Health is a key partner in this project. This essential book, used every day by paediatricians and other healthcare professionals, contributes widely to patient safety. This new edition means that users have the best possible information at their fingertips for treating children and young people.”

BNF for Children 2007 is published

2007-07-27: The third edition of BNF for Children (BNFC 2007) has been published

The third edition of BNF for Children (BNFC 2007) has been published. To review the changes made for this new edition please see What's new in BNF for Children 2007

BNF for Children 2007 Survey

2007-07-27: With this third edition of BNF for Children we are conducting a short survey to obtain comments from healthcare professionals about specific aspects of the publication.

BNF for Children has been constructed to meet the needs of healthcare professionals who look after children. Since the launch of the first edition of BNF for Children, numerous changes have been made to the layout and content of the publication as a result of feedback received from healthcare professionals. It is important to determine whether these changes continue to meet the needs of the users that BNF for Children aims to serve. We are also keen to identify areas where further improvements can be made. In this way the publication, in both paper and digital formats, can retain its relevance to clinical practice.

Whilst constructive comments on the content of BNF for Children are always welcome, with this third edition we are running a short questionnaire to obtain comments from healthcare professionals about specific aspects of the publication.

We would be grateful if you will spare a few minutes to complete this questionnaire about the digital version of BNF for Children available at bnfc.org. Readers wishing to comment on the printed version of BNF for Children should do so using the postal questionnaire inserted in the book.

Please click here to go to the questionnaire

Thank you for your help.

BNF for Children aligned with NHS drug dictionary

2007-07-11: The online edition of the BNF for Children now incorporates an interface to the NHS Dictionary of Medicines and Devices

The online edition of the latest BNF for Children (BNFC 2007), published earlier this month, now incorporates an interface to the NHS Dictionary of Medicines and Devices. This provides healthcare professionals with seamless access to BNFC content on the Internet using NHS dm+d codes, helping them to make the best treatment decisions for their patients.

The move is a fundamental step towards more efficient and safer prescribing practices and provides a means of directly accessing BNFC information from within the healthcare professional’s workflow.

The new interface can be accessed by appending an NHS dm+d code to a programmatically generated BNFC web address (URL). Once clinical systems have been configured to generate these URLs, the links between the NHS dm+d and BNFC will provide health professionals with a new means of accessing concise, authoritative and up-to-date prescribing information to support their clinical decisions.

The interface allows users direct access to BNFC information about a selected medicinal product from within a clinical system. As clinicians are working, prescribing or dispensing a medicine during a clinical encounter, it is now possible with a single click to access the relevant BNFC information for that medicine. Similarly, library or local formulary systems can use the interface to provide links from their material directly to corresponding BNFC content.

“Providing clinicians with the tools to make the best decisions for their patients is a key objective of the NHS Connecting for Health programme and closely parallels BNFC’s mission to provide excellence at the point of care,” says Dominic Vaughan, BNFC publishing director.

“With the ever-increasing pressure on clinicians, this development is an important step towards ensuring BNFC knowledge is accessible whenever and wherever it is required from within the clinician’s workflow.”

A more technical document providing details of the links created between the NHS dm+d and BNFC together with the format of the URLs for accessing the interface is available upon request (please contact us).

The NHS dm+d provides a common way of describing and coding all medicines and devices used within the NHS. It is expected to be used with all clinical information systems handling medicines information and is essential to support patient care across all sectors of the health service.

Revisions to the BNF for Children highlight importance of up-to-date information

2007-07-09: Updated advice on the management of serious and potentially fatal disorders

Unless doctors, nurses, pharmacists and dentists consult the latest edition of the BNF for Children (BNFC 2007), there is a real risk that children may not be given the right prescriptions for the medicines they need.

The warning comes from Professor Martin Kendall, Chairman of the Formulary Development Committee, at the launch of the BNFC 2007 which was published at the beginning of July.

BNFC 2007 has been fully revised and improved. The changes include:

  • Details of a new immunisation schedule for vaccination against meningitis and other fatal infections
  • Updates on the management of MRSA (meticillin-resistant Staphylococcus aureus)
  • New advice on the management of childhood obesity
  • Revised guidance on the management of children with Attention Deficit Hyperactivity Disorder (ADHD)
  • Updated advice on the management of the serious, potentially fatal disorders—asthma and epilepsy
BNFC 2007 is available in print and online. Further details about these and other changes can be found at http://bnfc.org

Dr Sheila Shribman, National Clinical Director for Children, Young People and Maternity Services added: “The safe treatment of children is at the heart of government policy on child health. The National Service Framework [NSF] for Children, Young People and Maternity Services stipulates that those looking after children need to be able to make decisions about medicines based on sound information. BNFC provides such information and, as such, is a key to the successful delivery of the NSF. I welcome this new edition.”

BNF for Children 2006 is published

2006-07-20: The second edition of BNF for Children (BNFC 2006) has been published

The layout of this second edition of BNF for Children (BNFC) has undergone numerous changes to improve the speed and accuracy of information retrieval. A great many of these changes have resulted from comments by users of the first edition. Independent market research provided further valuable insight from key users in the community and in secondary-care facilities. In addition, numerous changes have been made to the content.

BNF for Children is launched

2005-09-20: The BNF for Children is officially launched today

A new guide which will transform doctors' access to advice on children's medicines is being launched today at the British Medical Association.

The handbook – BNF for Children (BNFC) – is the first comprehensive information resource for doctors, pharmacists, nurses and other healthcare professionals on medicines for children.

The guide covers newborn babies to 18-year olds and gives a range of guidance, from choosing the best available drug to specific doses and formulations—information doctors normally have to research from multiple sources.

Doctors and other prescribers currently use the British National Formulary (BNF) – the 'drugs bible' – as their medicines reference manual. The BNF provides general information on children's medicines but, as prescribing for children has become more complex, healthcare professionals need a source of more specialist information.

Dr George Rylance of the Royal College of Paediatrics and Child Health, who chaired the BNFC formulary committee, commented:

"When treating children dosages must be tailored for each child, calculated by weight and age. Until now the information doctors needed to do this was not easily or readily available when they needed it—during a consultation for instance.

"Most drugs for everyday children's ailments are licensed for paediatric use. But drugs developed for adults are not always tested for use in children. For complicated or more serious conditions doctors often need to use drugs tested in adults which have not been specifically licensed for children (off-label prescribing), or which are not routinely available (unlicensed prescribing).

"The new guide will bring all this information together in one reliable source. It's a great step forward for children's medicine. For the first time, all doctors will have the latest advice at their fingertips."

The BNFC will play a key part in a European initiative, led by the UK, to develop more treatments for children and expand research and information in the field.

Ian Costello, lead editor of BNFC said:

"Updated every year the BNFC will continue to develop, including innovative treatments and new evidence as they become available. This guide will set a new standard—wherever you live in the UK, your doctor will have the latest information on the best treatment for your child."

Health Minister Jane Kennedy said:

"The new BNF for Children is a very exciting development and an important tool in improving the quality of prescribing medicines for children. This is why we are investing £1.8million in this project and ensuring that 175,000 copies of the BNFC are provided free of charge for doctors and other prescribers of paediatric medicines in the NHS."

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